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KMID : 0359720220400010060
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Journal of the Korean Neurological Association
2022 Volume.40 No. 1 p.60 ~ p.62
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Anti-Hu Antibody-Mediated Myelopathy Associated with Gastric Adenocarcinoma
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Park Ki-Seok
Kim Jae-Joon
Shin Dong-Hun
Shin Jin-Hong
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Abstract
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Anti-Hu antibody causes paraneoplastic syndrome of the nervous system. Most of the anti-Hu antibodies are found with small cell lung cancer, but can rarely be found with other cancers such as non-small cell lung cancer, prostate cancer, and breast cancer. We report a 57-year-old male patient with advanced gastric adenocarcinoma who had paresthesia and limb ataxia. Electrophysiologic study and imaging showed peripheral neuropathy accompanied with myelitis. Anti-Hu antibody was detected in the patient’s serum, leading to the diagnosis of paraneoplastic syndrome.
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KEYWORD
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Paraneoplastic syndromes, Adenocarcinoma, Stomach neoplasms
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